Assessment of Cervico-Vaginal Factors

The cervix is the canal that connects the vagina to the uterus. It measures approximately 3 cm and has important functions related to fertility:
• changing its consistency from thicker to thinner to allow the passage of sperm during ovulation;
• protecting the sperm from the acidic environment of the vagina;
• selecting the most mobile sperm for fertilization, leaving behind those with impaired motility;
• the sperm's capability: nourishment of sperm and separation of sperm components.

Any change in the cervix can lead to a fertility issue. However, only 5-10% of couples facing difficulties in conceiving have infertility caused by the cervical factor.

What are the causes?

Cervical problems that can lead to infertility can be differentiated into anatomical or functional. In both cases, the correct migration of sperm to the uterus and fallopian tubes is affected.

Anatomical causes include: developmental abnormalities, polyps, fibroids, cysts, cervicitis, cervical trauma

Functional causes refers to the modification of cervical mucus characteristics: quantity, consistency, acidity. Among these can be: insufficient estrogen release, the use of medications with antiestrogenic effects (clomiphene), infection of the cervical canal walls, formation of antisperm antibodies.

How do we diagnose?

The following tests are recommended for diagnosing the cervical factor of infertility:
• Postcoital test - studies the presence or absence of mobile sperm in cervical mucus after sexual intercourse.
• Microbiological cultures - to confirm if there is any bacterial infection.
• Cervical permeability test - a cannula is inserted to check if it passes easily or if there is any obstruction.
• In vitro immunologic test - it assesses the mucus-sperm interaction, along with the characteristics, the ability of sperm to pass through cervical mucus, and the presence of antisperm antibodies in both fluids.
• Cervicoscopy - the inside of the cervix is studied by inserting a camera.

Postcoital test

The postcoital test (PCT) is used to exclude the cervical factor of infertility by assessing the quality of cervical mucus and the survival of sperm after sexual intercourse before ovulation.

PCT involves the microscopic examination of a specimen of cervical mucus obtained before ovulation, from four to eight hours after sexual intercourse. The test is not painful. Results are released on the same day.

To obtain accurate results, it is important to observe the following conditions:
• The optimal period for performing the postcoital test is 24-48 hours before ovulation. Testing done well before or too late after ovulation is not considered valid.
• The partner should have normal sperm parameters.
• The postcoital test should be performed no later than 6 hours after sexual intercourse.

The test result will contain information about:
• Quantity and quality of cervical mucus
• Presence or absence of mobile sperm in cervical mucus

Book appointment

Prof. Veaceslav Moșin

Gynecologist, IVF Specialist

40+ years of experience

Consultation at the clinic

Dr. Tatiana Cebotari

Gynecologist, IVF Specialist

10+ years of experience

Consultation at the clinic

Dr. Dorina Iutiș

Gynecologist, IVF Specialist

10 years of experience

Monday	9:30 – 17:00
Tuesday	9:30 – 17:00
Wednesday	9:30 – 17:00
Thursday	-
Friday	9:30 – 17:00
Saturday	10:00 – 15:00
Sunday	-

Monday	8:30 – 17:00
Tuesday	8:30 – 17:00
Wednesday	8:30 – 17:00
Thursday	8:30 – 17:00
Friday	8:30 – 17:00
Saturday	10:00 – 15:00
Sunday	-

Monday	9:00 – 15:00
Tuesday	9:00 – 15:00
Wednesday	9:00 – 15:00
Thursday	9:00 – 15:00
Friday	9:00 – 15:00
Saturday	10:30 – 15:00
Sunday	-

Assessment of Cervico-Vaginal Factors

Any change in the cervix can lead to a fertility issue. However, only 5-10% of couples facing difficulties in conceiving have infertility caused by the cervical factor.

What are the causes?

Cervical problems that can lead to infertility can be differentiated into anatomical or functional. In both cases, the correct migration of sperm to the uterus and fallopian tubes is affected.

Anatomical causes include: developmental abnormalities, polyps, fibroids, cysts, cervicitis, cervical trauma

How do we diagnose?

Postcoital test

The postcoital test (PCT) is used to exclude the cervical factor of infertility by assessing the quality of cervical mucus and the survival of sperm after sexual intercourse before ovulation.

PCT involves the microscopic examination of a specimen of cervical mucus obtained before ovulation, from four to eight hours after sexual intercourse. The test is not painful. Results are released on the same day.

The test result will contain information about: • Quantity and quality of cervical mucus • Presence or absence of mobile sperm in cervical mucus

Book appointment

Consultation at the clinic

Monday 9:30 – 17:00 Tuesday 9:30 – 17:00 Wednesday 9:30 – 17:00 Thursday - Friday 9:30 – 17:00 Saturday 10:00 – 15:00 Sunday -

Consultation at the clinic

Monday 8:30 – 17:00 Tuesday 8:30 – 17:00 Wednesday 8:30 – 17:00 Thursday 8:30 – 17:00 Friday 8:30 – 17:00 Saturday 10:00 – 15:00 Sunday -

• Diagnosis and treatment of female infertility • Treatment of endocrine-dependent menstrual cycle disorders (endometriosis, polycystic ovary syndrome, uterine fibroids) • Pregnancy planning • Hormone replacement therapy in menopause and post-menopause.

Consultation at the clinic

Monday 9:00 – 15:00 Tuesday 9:00 – 15:00 Wednesday 9:00 – 15:00 Thursday 9:00 – 15:00 Friday 9:00 – 15:00 Saturday 10:30 – 15:00 Sunday -

Alternativa Clinic

Blvd. Cuza-Voda 31/1Chisinau, Republic of Moldova

Mon - Fri: 9:00 - 18:00; Sat: 10:00 - 15:00

All rights reserved © 2024 SRL FERTIL MED

Alternativa Clinic

Blvd. Cuza-Voda 31/1Chisinau, Republic of Moldova

Mon - Fri: 9:00 - 18:00 Sat: 10:00 - 15:00

All rights reserved © 2024 FERTIL MED SRL

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The test result will contain information about:
• Quantity and quality of cervical mucus
• Presence or absence of mobile sperm in cervical mucus

Monday 9:30 – 17:00

Tuesday 9:30 – 17:00

Wednesday 9:30 – 17:00

Thursday -

Friday 9:30 – 17:00

Saturday 10:00 – 15:00

Sunday -

Monday 8:30 – 17:00

Tuesday 8:30 – 17:00

Wednesday 8:30 – 17:00

Thursday 8:30 – 17:00

Friday 8:30 – 17:00

Saturday 10:00 – 15:00

Sunday -

• Diagnosis and treatment of female infertility
• Treatment of endocrine-dependent menstrual cycle disorders (endometriosis, polycystic ovary syndrome, uterine fibroids)
• Pregnancy planning
• Hormone replacement therapy in menopause and post-menopause.

Monday 9:00 – 15:00

Tuesday 9:00 – 15:00

Wednesday 9:00 – 15:00

Thursday 9:00 – 15:00

Friday 9:00 – 15:00

Saturday 10:30 – 15:00

Sunday -

Blvd. Cuza-Voda 31/1
Chisinau, Republic of Moldova

Blvd. Cuza-Voda 31/1
Chisinau, Republic of Moldova

Mon - Fri: 9:00 - 18:00
Sat: 10:00 - 15:00