Ovarian rejuvenation (PRP)
What is ovarian rejuvenation?
Ovarian rejuvenation is a procedure through which stem cells and ovarian follicles are reactivated to enhance the ovarian response to assisted reproduction treatments. The procedure takes place through the biostimulation of the ovaries with platelet-rich plasma (PRP) .
What is PRP (Platelet-Rich Plasma)?
It is plasma rich in platelets obtained from the patient's blood. After collecting a blood sample from the patient, it is subjected to centrifugation to separate the platelets from other blood components. Thus, a high concentration of platelets is obtained. At the same time, growth factors are released. These factors have the property of stimulating the body's mechanisms for repairing affected tissue , which in this case represents the ovaries .
When is ovarian rejuvenation indicated?
It is indicated in the following cases:
- Ovarian insufficiency;
- Reduced ovarian reserve;
- Failed or low-prognosis In Vitro Fertilization (IVF);
- Mature reproductive age;
- Increased rate of aneuploidy (abnormal number of chromosomes) of oocytes.
What are the steps of the procedure?
1. Consultation with the gynecologist and completion of the medical form
2. Signing the informed agreement for the procedure and performing an electrocardiogram (ECG) by the nurse
3. Consultation with the therapeutic doctor
4. The nurse draws 10 ml of blood from a vein to obtain platelet-rich plasma
5. Administration 10-20 minutes before the procedure: orally, a solution of Solket 80 mg dissolved in 100 ml of still water, or rectally, a Ketoprofen suppository
6. Administration 10-15 minutes before the procedure by the nurse under aseptic conditions, in the procedure room: LIDBREE anesthetic gel (heated to 37 degrees) in the vagina and posterior fornix
7. Performing the PRP procedure: injecting the platelet-rich plasma into the ovaries under ultrasound guidance
8. 30 minutes of rest after the procedure in day-stay hospitalization
9. Performing control ultrasonography (USG)
10. Issuance of the medical extract
11. Follow-up consultation with the gynecologist
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Infertility
• Infertility in couples
• Recurrent miscarriages and halted pregnancies
• Uterine factor: thin endometrium, endometritis, adhesions, polyps, uterine fibroids, etc.
• Ovarian factor: low ovarian reserve, polycystic ovary syndrome, ovarian cysts
• Hereditary and acquired thrombophilia
• Gynecological infections: chlamydia, mycoplasma, ureaplasma
• Menstrual disorders: painful, heavy, irregular, amenorrhea
• Specialization in endocrinology
Fertilizare In Vitro
• Pregătirea cuplului către fertilizarea in vitro
• Folosirea adjuvantelor pentru sporirea succesului FIV: anticoagulante, imunoterapie, terapie hormonală pre-FIV, ”scratching” endometrial, PRP (Platelet-Rich Plasma), irigații intrauterine, vitamine, suplimente nutritive
• Alegerea protocolului de stimulare ovariană, Mini-FIV, FIV în ciclul natural
• Monitorizare ecografică și hormonală a stimulării ovariene
• Eșecuri repetate ale procedurii FIV
• FIV la femeile după 40 ani
• Referire pentru procedura FIV către clinicile partenere din RM, Ucraina, România, Europa
• Conduita sarcinii după FIV